SELECT-LINE Cell Culture Services
Cost-Effective, Customizable Cell Culture Production for Established Hybridoma Cell Lines
The SELECT-LINE Services enable small- and large-scale cell culture for established cell lines. A variety of cell culture techniques are available, featuring the LAMPIRE OMNI C3® Cell Culture Bag. Additional services include ascites, roller bottle, and bioreactor production. To begin discussion about your project, please contact us today by
email or at 215-795-2838.
LAMPIRE OMNI C3® Cell Culture Bag Production
The next generation in cell culture devices, the LAMPIRE OMNI C3® Cell Culture Bag is constructed from a proprietary material that enables superior gas permeability and high surface area-to-media ratio, thereby permitting greater fill volumes and protein yield.
Prices include the use of LAMPIRE's standard medium. A medium of your choice may be substituted, but may incur an additional charge.
| Pricing Schedule |
| OMNI C3® Cell Culture Bag Production |
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Note: The OMNI C3® Cell Culture Bag may be purchased individually for use in your laboratory.
Ascites Production
Ascites production employs Balb/C mice, with ascites fluid collected and pooled at the end of the project. Each mouse yields approximately 2-5 ml ascites. Alternate strains of mouse may be used, but may incur an additional charge.
Production volume is approximately 2-5 ml ascites per mouse.
Prices include husbandry of mice for up to 35 days, with 1 injection of cells and up to 3 taps.
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| Cell Line Expansion |
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Note: AAALAC regulatory guidelines require written assurance that the proposed laboratory animal use is scientifically justified and that in-vitro or other methods have been evaluated and found unsuitable.
Roller Bottle Production
Roller bottles are a cost-effective alternative to large-scale antibody production using murine ascites. Typical lot sizes are 1-10 g of antibody.
Production volume is approximately 20-50 mg/liter of roller bottle culture for an average producing cell line.
Prices include the use of LAMPIRE's standard medium. A medium of your choice may be substituted, but may incur an additional charge.
| Pricing Schedule |
| Roller Bottle Production |
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Note: Bulk discounts are available. Please inquire.
Bioreactor Production
Bioreactor formats include hollow fiber, ceramic core perfusion, stirred tank, and microcarrier systems.
Hollow fiber systems are ideal for non-adherent cell lines and work well with most cell lines tested. Production volumes of up to 300 mg per day are possible and the system can be used to grow and harvest cells and cell products other than antibody.
Stirred tank systems are useful for both adherent and non-adherent cell lines lines and are capable of producing 1-3 g antibody per week.
Microcarrier systems employ packed and fluidized bed techniques to increase the surface area for cell attachment in stirred tank bioreactors. Production volumes of 500-1000 mg per day are possible.
Prices include the use of LAMPIRE's standard medium. A medium of your choice may be substituted, but may incur an additional charge.
| Pricing Schedule |
| Bioreactor Production |
Please Inquire |