Monoclonal Support Services
To begin discussion about any of these services, please contact us today by email
or at 215-795-2838.
Cell Line Optimization
LAMPIRE will take an existing cell line that has been provided and optimize the media formulation for growth and production of antibody. Price is dependent upon the number and type of media formulations to be used for the optimization. Please contact our Customer Support Staff for further information.
Adaptation to Serum-Free Culture
LAMPIRE will take an existing cell line and adapt the cell line from a culture media containing serum to a serum free media culture. Price is dependent upon the type of media to be used for the adaptation and the original serum content of the media. Please contact one of our Customer Support Staff for further information.
Cell Bank Production
LAMPIRE can make Master and Working Cell Banks of any size to fit your needs. Cell bank reports will be generated and sent for review. Please contact our Customer Support Staff for services such as storage and annual testing for Viability, Doubling-Time, and Antibody Yield. Related fees are outlined below in Cell Bank Storage.
Cell Bank Storage
LAMPIRE has the capabilities of storing cell banks at our facilities. LAMPIRE recommends that all cell banks that have been created, whether by LAMPIRE or another contractor, be stored at two different locations for safety purposes. LAMPIRE can test the cell banks on a yearly basis as well. LAMPIRE will expand 1 vial and determine the viability 24 hours, 48 hours, and 96 hours after thaw, the doubling time and antibody yield with results being reported in a one page summary.
Sterility and Mycoplasma Testing
Sterility testing results are based on CFR 21 or USP XXIII. Generally, 14 days at 30-35íC in fluid thioglycollate and 14 days at 20-25íC in Soybean Casein Digest medium. Mycoplasma testing reports via indirect DNA Hoechst Staining and Agar and Broth media isolation of culturable strains of mycoplasma.