Pharmacokinetic

With LAMPIRE’s state of the art vivariums and expert technical staff we offer a wide variety of customized services.  LAMPIRE takes great care to make your research goals are our top priority through attention to detail and communication.  LAMPIRE offers our clients the highest quality services backed by AAALAC accreditation, OLAW assurance and licensure by the USDA.  LAMPIRE’s core value of exemplary animal care is the foundation for high quality research.  Coupled with exacting attention to drug delivery protocols, sample collection and data integrity, LAMPIRE sets the standard for PK/ADME studies.  
 

Multiple Species
 Guinea Pigs / Mini-Pigs / Mice  / Rats / Rabbits

In Vivo PK Services...Read more

With LAMPIRE’s state of the art vivariums and expert technical staff we offer a wide variety of customized services.  LAMPIRE takes great care to make your research goals are our top priority through attention to detail and communication.  LAMPIRE offers our clients the highest quality services backed by AAALAC accreditation, OLAW assurance and licensure by the USDA.  LAMPIRE’s core value of exemplary animal care is the foundation for high quality research.  Coupled with exacting attention to drug delivery protocols, sample collection and data integrity, LAMPIRE sets the standard for PK/ADME studies.  
 

Multiple Species
 Guinea Pigs / Mini-Pigs / Mice  / Rats / Rabbits

In Vivo PK Services
• In-house vascular and intestinal cannula implantations
• PK/PD Modeling
• Micro-serial sampling 
• Multi-dose/ dose proportionality/drug-drug interaction studies/food 
   consumption studies
• Intravenous (IV), Oral (PO), Subcutaneous (SC), Intramuscular (IM), 
    Intranasal, Intraocular, dermal, sublingual, osmotic pump and or 
    implant dosing


 ADME Services
• Bile duct cannulation with duodenal return/ with or without JVC
• Tissue distribution/brain penetration
• Blood, urine, feces, lymph and tissue sampling 
• CSF collection in mice and rats
• Tissue perfusion and collection
• Lab animal metabolism caging
 

PK Support Services
• In-house surgical model development
• In-house vascular and non-vascular catheterization
• Soft tissue procedures
• Bio specimen collection/tissue perfusions
• In house formulation: including single, cassettes and vehicle 
    preparations
• Brain region isolation 
• Lymph node collection

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